DPCstruct | MC63285

Metacluster Properties and Pfam Annotations

Number of structural domains216
Mean domain length (aa)167 ± 43 aa
Standard deviation of domain lengths42.66
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score86.11
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)22.18
Pfam Score99.46
Assigned Pfam label(s) CL0029- PF02586

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A158L1V0 21-193 EDGQYVVRPMRYQCRLAGKPANYDVKFPGTYNARRDNLEGFWKPLFGHTHGVMLVDVFYENVSKAKWEGTLLEAHDKDENVVLEFRP…
A0A2S5TQ51 1-115 CVVPFTSFSEWDAAIKAPAWFALDDSRPLAFFAGIWTPHWTSVRKARTGIETADLFAFLTCEPNAVVAPIHPKAMPVILTTQDEVEM…
A0A847E6W1 3-101 None
A8J4M2 160-361 None
A0A0D3DVB9 33-219 None
A0A421JS63 5-134 None
A0A1G4QSN6 17-158 None
A0A7S4PEI2 10-141 None
A0A167LFT1 724-921 None
A0A2A2K4Q1 32-198 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.