DPCstruct | MC63195

Metacluster Properties and Pfam Annotations

Number of structural domains359
Mean domain length (aa)171 ± 30 aa
Standard deviation of domain lengths30.40
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score86.54
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)19.15
Pfam Score97.55
Assigned Pfam label(s) CL0649- CL0123- CL0124- PF04675- CL0193

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7T5RKB2 8-137 LLTLAEDAGLEVDILNGRPGVYTARYAPGTDEDRYRKLLSELQNVSEEKRTARFRATIAIYDPSNDKVRTCEGIYEGRIALEPIGNN…
A0A2E1VHV0 4-173 ALILASESQYKKNILERLEIAFSTEAPAINETPRPGESARALSSRLAQRKAEKIAARYPDAIVISTDQSAEVHGVILGKPATIENAR…
A0A6J5VP47 50-220 None
A0A837PZM3 5-141 None
A0A7X9KYT3 240-426 None
A0A2E4HLK0 10-190 None
F8JFF8 6-194 None
A0A7R9A6X4 29-131 None
A0A1Y2HAF1 218-414 None
A0A0G4H097 24-223 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.