DPCstruct | MC63188

Metacluster Properties and Pfam Annotations

Number of structural domains134
Mean domain length (aa)131 ± 21 aa
Standard deviation of domain lengths21.06
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score77.22
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)30.26
Pfam Score98.51
Assigned Pfam label(s) CL0207- PF00183- PF16712

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3L6QAT1 327-465 CERVERVVVSDRLGDSTCCVITAKTEKIMRAQQLSSPSLLGYVTKLTMEINPVSPVMKKLRKRAEANRNDKFVKDTVILLFETTLLT…
A0A7Y0WYQ7 26-147 KETEEEFKSVVERTKSYLGDRVKDVRTTFKLASTPAVVVTDDYEMGTQMAKLLAAAGQAVPEVKYIFEINPEHELVKRMADEADEEA…
R7UAU2 2-86 None
A0A2V2W6U6 18-148 None
M1A3V7 125-238 None
A0A6I8NVF5 203-346 None
K8EXD6 1056-1206 None
A0A7S1XR15 1-116 None
A0A1R3L475 232-361 None
A0A226F3D9 432-580 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.