DPCstruct | MC63168

Metacluster Properties and Pfam Annotations

Number of structural domains635
Mean domain length (aa)152 ± 31 aa
Standard deviation of domain lengths30.66
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score83.98
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.49
Mean intra-cluster sequence similarity (%)15.98
Pfam Score98.79
Assigned Pfam label(s) CL0023- PF20131- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2X2DMB5 1-164 MLVSFGAKNFASFKEGFDISFRFGNACPEQISQGKSISNIICVKGANGAGKTNILKALNFISSFISRSFDIKPDSHILFDSYFSSIT…
A0A101X6K8 1-133 MITRVEVENFRSIVKGKAIITEGINFIHGPNGAGKTSLLEAIAIALYGSEWVRGRYRLGDLVRRGASSSVIRVEYVGIDGRRYLVQR…
A0A524RR97 23-197 None
A0A0B8NLC1 1-99 None
A0A1W9WY55 2-122 None
A0A837Q1S9 6-174 None
R6VK16 317-470 None
A0A1I5XR42 2-130 None
A0A1Q6K9B6 1-132 None
I1CDT8 60-176 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.