DPCstruct | MC63129

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)101 ± 8 aa
Standard deviation of domain lengths7.61
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score93.95
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.93
Mean intra-cluster local Distance Difference Test score0.89
Mean intra-cluster sequence similarity (%)39.78
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5E6NJH1 2-107 LKSYCLNSVASRHNMDDLSEHYLGYTTTHFTDIAGKGKKQITFNQVSIDDGAPYACEDVIVTHKLNEVLAQELVNYATLYKLYQTLE…
A0A377LQE1 180-284 LESYILDSVAGRHDMDSLSDRWLKHKTITFEEIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQLHLKMWPKLQKHEGPLNVFQNIE…
A0A0G1NIM0 449-553 None
A0A1E3H7I1 184-288 None
A0A832NLT4 324-429 None
A0A5B5VW15 72-175 None
A0A5A7MSX5 1-106 None
A0A7R9RC42 30-134 None
A0A7Z9IPB6 4-89 None
A0A447J974 1-90 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.