DPCstruct | MC6310

Metacluster Properties and Pfam Annotations

Number of structural domains180
Mean domain length (aa)279 ± 64 aa
Standard deviation of domain lengths63.79
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score80.43
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)29.57
Pfam Score79.89
Assigned Pfam label(s) CL0257- PF21183- PF21184- CL0010- CL0192

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
I1BH38 104-330 NQDSFIDSVKTDHVQFKPIGEKIHEYTREVKHGNEYFEIYKSSFSSQKFREYHARMKIFVLLFIEGGSYIEDDDEKWEIFTIFKREG…
A0A137NXI3 75-378 QPAKPPANTPIIPIEPSLSHKKTFKEIPSPYSTSIKSCVFDRVEIDTPSQSFYPSALVTGNKVHICEICFKYFNDFGTLVHHRTNCS…
A0A7E5WXR2 2-180 None
A0A162PKL5 197-471 None
S4RP37 70-339 None
A0A368FEP8 37-300 None
A0A1S8VW73 4-237 None
A0A5J5C8D2 2-262 None
A0A3P7DDZ1 32-259 None
H2B2C1 131-429 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.