DPCstruct | MC6306

Metacluster Properties and Pfam Annotations

Number of structural domains1660
Mean domain length (aa)253 ± 41 aa
Standard deviation of domain lengths41.01
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score86.76
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.40
Mean intra-cluster sequence similarity (%)12.78
Pfam Score84.66
Assigned Pfam label(s) PF19527- CL0126- CL0672- CL0020- CL0056

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A086JLR3 696-928 NMVESGKVEGEKGRHFAVFEDPFQKPCYLFALVAGDLKSISQSFTTMSGRNVKVSIFSEPEDSSKLTWALESVLKSMKWDEERFGRE…
A0A485M593 35-283 VLVLCLLAGTPQAQEYRVMDGPGIQVMYADPSLELSAREVIGRYPSIKEGLESVFLWEMDFHPRVLLVADRRSFIMMAGHEAYVAYA…
A0A7R9PQ32 224-485 None
A0A1W1XF26 181-411 None
A0A6B1GFU9 158-397 None
K8EE20 12-422 None
A0A1M5EPK2 782-982 None
A0A212T4D1 21-240 None
A0A1D1W7M0 255-552 None
A0A7R9Q2B9 451-702 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.