DPCstruct | MC63021

Metacluster Properties and Pfam Annotations

Number of structural domains147
Mean domain length (aa)119 ± 23 aa
Standard deviation of domain lengths22.77
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score71.63
Mean fraction of residues predicted as intrinsically disordered0.49
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)35.53
Pfam Score95.32
Assigned Pfam label(s) PF20624- PF12374- PF00751

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183A9M3 311-435 None
A0A183PKG9 347-426 None
A0A224YV99 27-147 None
A0A183V8Q6 1-116 None
A0A183VEN8 12-131 None
A0A1I8B3D6 252-390 None
A0A834P2M2 130-265 None
J7FCF0 1-138 None
A0A1W4WR30 2-137 None
A0A6J1RC21 4-95 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.