DPCstruct | MC62934

Metacluster Properties and Pfam Annotations

Number of structural domains41
Mean domain length (aa)137 ± 20 aa
Standard deviation of domain lengths19.85
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score88.46
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)18.60
Pfam Score100.00
Assigned Pfam label(s) PF01322

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7I8MQT4 17-150 VAGIAHAQFSKPEDAIRYRQSVMVLIVHHFKQMGAVVQGKANYDKASFEDHTKLVHTLSTMPWEAFMTPDSDTGKTDLEPSALKNKD…
A0A645EZD3 2-125 IRYRKAGYAFMNWNMAKLKAMLDGSVPFNKDQALAATTSINSTVNSGMGALYTPGSDKDAGNEKTRLKSEFFTQPDKVKEVAGAYRV…
D3SFU5 1-186 None
A0A2T8HQH8 86-230 None
A0A523CL41 3-149 None
A0A6M1LLT5 1-146 None
A0A355AWP7 2-115 None
A0A258S8K0 3-105 None
A0A517QGP2 13-146 None
A0A1E3H0A2 11-126 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.