DPCstruct | MC62878

Metacluster Properties and Pfam Annotations

Number of structural domains70
Mean domain length (aa)164 ± 26 aa
Standard deviation of domain lengths26.17
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score82.61
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)29.88
Pfam Score97.50
Assigned Pfam label(s) PF04290- CL0182

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1G7HHL4 14-141 SGMIFFLQQPTLPLTIPVQLVLTQTQSFVLLAIPLFMFAGNLLNESGITYRLMKLSSVLAGHMRAGVAQVNTVLAAMMGGITGSAIA…
A0A3D4EGW7 5-183 ILIGVFVVLLISGLPVALCLGISALVSVLQMDLPAMTLAINSNAALSKVVLEAIPFFILGGNIMEKSGISRKLIDFASAFVGHIKGG…
A0A101FL54 1-122 None
A0A379GIZ6 2-153 None
A0A1E3GYE0 239-371 None
A0A0E8C4B8 1-144 None
A0A562ER74 2-132 None
A0A0B8NVU8 220-385 None
A0A1Q9C216 441-674 None
A0A4U5JA94 146-335 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.