DPCstruct | MC62873

Metacluster Properties and Pfam Annotations

Number of structural domains66
Mean domain length (aa)224 ± 43 aa
Standard deviation of domain lengths43.21
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score86.22
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)27.72
Pfam Score56.77
Assigned Pfam label(s) PF06883- CL0410- PF04563- PF04567- PF04565

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
O28392 1-173 MRKCRVYINGALVGFHDNGEELANKIRELRRKGRISNQVNVVYYPDSNEVRINTDAGRARRPLIVVKDGKPLVTPEHIEKIKKGELT…
A0A6P5RJD1 23-223 THVTTDEEESPLISLCYCLGVEGLEVLSGEELHTPYSFLVLFNGNILGKHRKPQHFAAAMRKLRRAGKIGEFVSVFVNEKQHCVYIA…
A0A2K3NLS5 1-190 None
A0A6S8SMV0 231-475 None
I1CVV8 474-749 None
A0A7S0MES3 83-355 None
A0A835Y177 568-789 None
A0A1A9VXS4 2-188 None
A0A0B1PSN9 89-348 None
A0A5E4QCT5 1-156 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.