DPCstruct | MC62859

Metacluster Properties and Pfam Annotations

Number of structural domains493
Mean domain length (aa)135 ± 26 aa
Standard deviation of domain lengths26.44
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score68.67
Mean fraction of residues predicted as intrinsically disordered0.44
Mean length-normalized TM-Score0.24
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)26.47
Pfam Score99.84
Assigned Pfam label(s) CL0511- CL0265- PF13865

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0N5AGL5 8-133 EECYKCHEVGHFARNCPNQSDGARRGGGTGECFSCGRKGHFARECPNGRHPGGYGGYGVRSRNTECYQCGGMGHVARECPSSRRGSS…
A0A0D2FHU8 216-330 PAVCLACLRADHTEQLCPEKTCQYCAAVGQHSSRLCPKIRRCAKCRERGHTAESCTANLGVTTVPCDLCGSLKHLEDACPHRFFPAE…
A0A7S4RRJ9 157-264 None
A0A6J1A8A1 249-414 None
A0A819Q6H4 87-214 None
A0A0N1I8Z8 5-107 None
A0A397EZL3 183-293 None
A0A1S3P8R7 10-123 None
A0A4Z0Z603 120-264 None
A0A673WA36 15-136 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.