DPCstruct | MC627

Metacluster Properties and Pfam Annotations

Number of structural domains31
Mean domain length (aa)100 ± 7 aa
Standard deviation of domain lengths7.42
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score83.26
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)28.67
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6B2M5L8 392-488 GAIGLANNWFWLDWFGYFNVAHESWTYHQQNHWLHPIGDNPENIVFWDSGMEAFWWTSSSFYPFAFRFSDGCWLYYQKDSMDPRRFY…
A0A7X8Z243 58-155 GWDAGYTAIGGGWRRLGWFGDYVPMSDWIFHNKHGFWYPAPSSTPQNIWFYTQDMGWLYTSSTQYPFLYRANDGAWLWYNGSTNPRW…
A0A2E4AYB7 1-93 None
A0A2E4ZUH9 1066-1160 None
A0A2E4ZYA5 289-384 None
A0A2E6TBD8 742-839 None
A0A2E6THP7 694-797 None
A0A496Q272 209-324 None
A0A6B2M5E8 14-105 None
A0A3B9FLV3 203-302 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.