DPCstruct | MC6265

Metacluster Properties and Pfam Annotations

Number of structural domains408
Mean domain length (aa)298 ± 69 aa
Standard deviation of domain lengths69.10
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score75.63
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)14.73
Pfam Score73.78
Assigned Pfam label(s) PF02161- CL0031- PF02159- PF00104- CL0167

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A815BUH2 40-335 None
M7B978 256-573 None
A0A7I8WNE4 18-372 None
A0A182UQC1 118-434 None
A0A672R3D3 45-364 None
A0A232F5K2 65-451 None
K1R4B8 290-539 None
H3FI28 17-448 None
H3EMD1 90-451 None
H3EM90 600-961 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.