DPCstruct | MC6265

Metacluster Properties and Pfam Annotations

Number of structural domains408
Mean domain length (aa)298 ± 69 aa
Standard deviation of domain lengths69.10
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score75.63
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)14.73
Pfam Score73.78
Assigned Pfam label(s) PF02161- CL0031- PF02159- PF00104- CL0167

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1B0B573 6-205 ESLEFQKIWLWQQYAARVTPGVQRVVEFAKRLPGFCDFTQDDQLILIKMGFFETWLSHVARLVKDSTLTFDDGTYLTRQQLEIIYDT…
A0A673U5W0 25-311 MNQDAVQNERQPRSTAHVRLASMESAAERRLEPLAAPRGPTPVSAARGLGHHFMASLITAETCAKLETEDADENIDVTSNDPEFPSS…
A0A7R9KN42 219-449 None
A0A7R9KML8 42-353 None
A0A7R9KJT5 24-267 None
A0A7R9KC99 19-364 None
A0A7R9KRQ4 1-180 None
A0A7R9KB58 96-277 None
A0A835CUQ7 311-518 None
A0A835CTS5 217-416 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.