DPCstruct | MC62649

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)110 ± 18 aa
Standard deviation of domain lengths17.79
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score87.76
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.86
Mean intra-cluster local Distance Difference Test score0.87
Mean intra-cluster sequence similarity (%)53.95
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A853M956 1-124 MDFRGKDGQPFPAWTDAESLFEAWKKCTAGRPCDCTGLTYDKLRGGSGIQWPCNTEHPDSTERLYVDAKFWATPGYCEAYGKDLITG…
X0K536 319-420 EFKNKEDEPLTPWTEPEEVFEAWKRLSAGRPCDYTGMSYAKLTGGSGIQWPCNDQYPVGKERLFDDGVFFTDIDYCESYGHDLQTGV…
A0A179UN63 234-354 None
X7YDJ4 270-382 None
H6RMJ4 93-195 None
A0A0J8CH16 23-126 None
A0A1J9R8X1 311-400 None
A0A1G8NRR1 37-122 None
A0A4Q4UKI5 532-648 None
A0A0D9NQK2 302-458 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.