DPCstruct | MC62643

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)74 ± 17 aa
Standard deviation of domain lengths17.02
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score73.92
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.87
Mean intra-cluster sequence similarity (%)52.84
Pfam Score100.00
Assigned Pfam label(s) CL0229

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A287U5D2 224-290 DTWEVRCVCGAQDDDDERMVACDACDVWHHTRCVGIADSEAVPPLFLCILCGGALLAAGPILEEALT
A0A2P2MM78 141-195 MERGIERWTVHCSCGAKDDDGERMLACDSCGVWQHTRCSGIPDCDSVPARFICHR
A0A2U1MVK7 1128-1174 None
A0A2G5DU39 428-530 None
C1MLV0 255-347 None
A0A545V2R8 277-368 None
A0A2G2X1Z5 51-115 None
M1A5Z2 185-256 None
A0A7S3F672 376-434 None
A0A1D2AFL4 994-1049 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.