DPCstruct | MC62636

Metacluster Properties and Pfam Annotations

Number of structural domains188
Mean domain length (aa)248 ± 39 aa
Standard deviation of domain lengths39.12
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score80.51
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)16.67
Pfam Score99.36
Assigned Pfam label(s) PF01544- CL0016

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A178EC87 10-294 RALAEFAQKISELTQTAVDNRKYVLVEKLQAWMREPSSSQLDKQYRTNTERLLRAAYPTKDFLPIEPWRINGKGHKCSLVVFSILLD…
A0A446BQB9 2-229 WRQIKGIEVTSEFRGVKFRFVPEGSLASVMSKEAIREELDDDDLPWTPELDCLVNFIHSRAQKLFAITVRYVGLTPLELRKAMKAFM…
A0A3L6NDZ3 25-238 None
A0A1Q5TMA2 140-393 None
W2RYR9 9-242 None
A0A010SBM6 52-351 None
A0A423VFR6 27-271 None
A0A6A5R0Y7 20-234 None
A0A4Q4W6P5 15-216 None
A0A3L6N4M6 21-288 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.