DPCstruct | MC62497

Metacluster Properties and Pfam Annotations

Number of structural domains78
Mean domain length (aa)312 ± 67 aa
Standard deviation of domain lengths67.24
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score73.97
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)26.46
Pfam Score97.44
Assigned Pfam label(s) CL0023- CL0431- CL0060- CL0123

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A845S4A6 11-250 NPLPKIVKTFKKDFDIIFFDEFQITNIADAMILGKLLEQFFSNNIFIITTSNVKPDDLYLGGLQRDQFLPYIENIKDNTLVYSLNSG…
A0A3P9M7I3 36-330 QSLPQRRLGKMFTYDPISPVAMEIANETSLLCFDEFQVTDIADAMILKQLFGTLFKTGVVVVATSNRCPDDLYKNGLQRDTFLPFIH…
W7IL88 395-615 None
C1E3X1 185-643 None
A0A1I8FKM4 59-300 None
W4GJS9 29-291 None
A0A061DEF5 482-914 None
A0A6P5FRZ5 274-479 None
K2SGK2 6-265 None
A0A7S1FKH8 66-447 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.