DPCstruct | MC62422

Metacluster Properties and Pfam Annotations

Number of structural domains2
Mean domain length (aa)204 ± 2 aa
Standard deviation of domain lengths2.00
Length coefficient of variation0.01
Mean AlphaFold2 pLDDT confidence score91.60
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)33.10
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
X1I5Z7 1-206 MTIESLPAAEITPSRITLDYLERYERVSHFYPHHFRERKFRKVEIDREQVVKVLREYNRRIEAPQKVMENIEMLLDENTYTVVTGQQ…
K9RIU3 571-772 NHRNWNSIYNSIRQRNYPRHKLAELLKKQAETWGNSKEVKANIDKLLDSQTVAVVTGQQVGILGGPVYTLYKALGAIKLARVLSEQG…

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.