DPCstruct | MC62420

Metacluster Properties and Pfam Annotations

Number of structural domains469
Mean domain length (aa)196 ± 31 aa
Standard deviation of domain lengths31.38
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score83.69
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)17.36
Pfam Score96.84
Assigned Pfam label(s) PF03782- PF04885- PF06119

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2R5GFU4 123-330 None
A0A2R5GDM0 260-474 None
X1WHS9 1758-1969 None
A0A553QM28 164-352 None
A0A4Z2C6Y9 19-234 None
O75443 22-231 None
A0A7J5XFZ8 17-195 None
A0A0N4XRA0 1-112 None
A0A2V5PFC1 314-539 None
A0A7C7M916 156-339 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.