DPCstruct | MC62395

Metacluster Properties and Pfam Annotations

Number of structural domains307
Mean domain length (aa)103 ± 23 aa
Standard deviation of domain lengths22.73
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score80.81
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)26.80
Pfam Score99.44
Assigned Pfam label(s) CL0125- CL0144- CL0229

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A4W0P3 4-94 CDHSEAVQPVPESGVNVSASCEDCGNMDENWVCLHCYKTLCGRFAKEHMLQHSSAAGHQVVLSAADLSTWCYGCDSYVDNDKTQAAK…
A0A453K3F3 1-59 CLRCHHPSENWLCLICKDVLCSRFINKHMLYHYQETGHCIALSFSDLSVWCFACDSYLD
A0A6G0XKB9 16-137 None
A0A7M5UR84 280-365 None
A0A803J7U7 595-730 None
F4PVY6 142-284 None
F4PS83 5-117 None
A0A2J8AFZ5 118-244 None
A0A6U1B433 13-141 None
L0DG64 1-87 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.