DPCstruct | MC62384

Metacluster Properties and Pfam Annotations

Number of structural domains2078
Mean domain length (aa)136 ± 26 aa
Standard deviation of domain lengths25.70
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score81.54
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)16.47
Pfam Score97.27
Assigned Pfam label(s) CL0276- CL0029- CL0063- CL0123- CL0373

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
C5L2S7 13-143 GGRHLSLDIFSDSRNKNALICHLAPLLQRVVKRPMDDKNGLIWKEGDIADQVVFVVRGQVGVEAPLENTQEETKGNAPRPPLWFYKE…
A0A3M3GGY6 82-157 ELTVLKINIPANTALKWHSHPIPNAAYVASGEITVEKRDSNKEIRLKKGDALAEMVDIVHRGKTGDTPVELIVFYA
A0A520QNP0 90-224 None
A0A356C141 4-100 None
A0A4R6SVJ2 15-159 None
A0A1M5R1Z6 41-140 None
A0A819QKK7 399-499 None
A0A521VTA1 1-101 None
A0A7R9XRQ7 313-477 None
X4ZMX5 134-239 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.