DPCstruct | MC62372

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)134 ± 24 aa
Standard deviation of domain lengths24.25
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score83.39
Mean fraction of residues predicted as intrinsically disordered0.40
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)29.97
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
U7QL66 1-148 MNINHSVCSLAVTCLFFSITNTAQAATFTRFAEGLQNARGLTFGPDGELYVAEAGIGGGSTSSSSIPSPNIPGLDLYLGNTGAVSKV…
A0A7C2WHT3 421-524 VASGLDNPRGLAFGPDGSLYVAEAGRGGESPCIAGPEGNEICYGLSGALTRVADGAQERVVTGLPSLAQADGGAALGPHDVAVRDDG…
A0A2D7PRL9 128-239 None
A0A535ETV8 417-560 None
A0A0P4V4E1 1-124 None
A0A2N5K643 48-200 None
A0A2T1CSP6 216-337 None
A0A1I2CLJ2 3-128 None
A0A7W0SFN1 3-98 None
A0A1Z9XZS1 73-202 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.