DPCstruct | MC6235

Metacluster Properties and Pfam Annotations

Number of structural domains29
Mean domain length (aa)75 ± 7 aa
Standard deviation of domain lengths6.82
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score91.26
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.90
Mean intra-cluster local Distance Difference Test score0.88
Mean intra-cluster sequence similarity (%)45.56
Pfam Score100.00
Assigned Pfam label(s) CL0061

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A376VFE6 100-173 YFVDPCKLLLTTPGIDAETGEYSDFGVPATILAHYLRENGIVPEKCDLNSILFLLTPAESHEKLAQLVAMLAQF
A0A447J139 11-83 IFVDPCKLLLTTPGIDAKTGNYEAFGVPATILANYLRENNIIPEKCDLNSILFLLTPAESMAKMQHLVAQIAR
A0A365VPP6 44-115 None
A0A447QJ10 1-59 None
A0A7K4BFA5 339-417 None
A0A377BZR0 6-84 None
A0A447TPN5 80-162 None
A0A7I8CHL0 179-258 None
A0A6N8KAJ1 52-126 None
A0A223RNQ4 607-676 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.