DPCstruct | MC62325

Metacluster Properties and Pfam Annotations

Number of structural domains188
Mean domain length (aa)272 ± 42 aa
Standard deviation of domain lengths42.09
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score83.96
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)11.92
Pfam Score72.28
Assigned Pfam label(s) CL0126- PF09458- CL0559- CL0005- CL0726

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A849QJL9 93-350 FPLEIGEVSVDHNWKRVAFNDTFIDPVVVANPLSYNGGDPAVLRIRNVDNTGFDIRVQEWDYLDGIHAEETVGYMVMERGAYTLPDG…
B5GVW9 120-356 PTVVASEWSADKEVATATCPAGTNLVGGGQDARLRVNGYDNVIDGVEANAPSPDTPNSWKVQLHLGQARAFAMCTAEAPMPTVVASE…
A0A1J9RES6 1001-1270 None
A0A7M5UQF2 353-724 None
A0A1T3NN51 490-887 None
A0A117VJD3 691-974 None
A0A0G4H163 173-445 None
A0A0G4HUD1 112-467 None
A0A7R8X5E8 14-287 None
A0A3A5HCM8 104-319 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.