DPCstruct | MC6226

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)89 ± 6 aa
Standard deviation of domain lengths6.38
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score82.55
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)24.03
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2J9E9S1 3-86 RQWPTYSDTNGNYVYALPIKAIRQTVDGYAYASFDGDNDDQYLSAQFMTIFRPVVGGYLFNSASGELLYMSKTTFEAQYSAQTT
A0A2P5IIE4 6-85 STNYPRWRSHKVVQAFQIAQINHAPDGAALSPSDPQLASVQVNADWVNKHNPQVGGFYVIYGDSYASYSPKEAFMDGYSL
A0A7C1S286 14-108 None
A0A7Z3BK44 4-86 None
A0A526VKE2 2-93 None
A0A377BFZ3 13-102 None
K1XCC1 25-110 None
A0A644RKN0 6-99 None
A0A1M7YP46 23-116 None
A0A7U1H3X6 5-88 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.