DPCstruct | MC62240

Metacluster Properties and Pfam Annotations

Number of structural domains42
Mean domain length (aa)188 ± 30 aa
Standard deviation of domain lengths30.33
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score82.96
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)66.90
Pfam Score80.03
Assigned Pfam label(s) PF10524- CL0263- PF00859

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5E4BSJ9 17-187 IEALLPHVRAIAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLSEKPEIKQKWASRLLAKLRKDIRQEYREDFVLTVTGKKHPC…
A0A401SYJ1 145-321 IEALLPHVRAIAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLSEKPEIKQKWASRLLAKLRKDIRQEYREDFVLTVTGKKHSC…
T1GCL7 1-176 None
A0A1I8FBQ4 49-162 None
A0A7J6BG17 9-218 None
H3AMN7 1-126 None
A0A7F8R8N2 118-349 None
A0A4Z2J2E1 105-303 None
A0A1D2N8V5 1-145 None
W5JRX9 5-152 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.