DPCstruct | MC62226

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)164 ± 23 aa
Standard deviation of domain lengths23.05
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score83.36
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)29.50
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6T1DER4 1-213 AQAVAAQGPPPLCQRVVRASATQVAAMPSYYETIDGEKLDKAIIDECRKAVEGQGDGRVSKEDAAKVFAKVEDGGKETRCERWTMRY…
A0A7C5INT1 1-155 MAEYKTINGVKYDKPLLEAAEKAIEGVGDGRVSFDDAKAIWADAMEDGKITKVEVRTIKYILENYKCTDKGREFLQGHVFRSIGGVI…
A0A812K0H0 1-173 None
A0A7S2KHA3 1-165 None
A0A2C6CT59 1-148 None
A0A812Q6F6 12-146 None
A0A5E8A1G3 71-208 None
A0A7S4SS10 92-253 None
C1N6W3 2-186 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.