DPCstruct | MC62156

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)330 ± 50 aa
Standard deviation of domain lengths50.25
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score76.72
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)27.45
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
U9UPU2 2-340 CNKCLEFMDKKENRNFQVAYRIELLPNNNQKEWEYAIQLDPVIWFDMLYNLSGDLPNTLKAARSYVNSVRRKYKLPAPIEPTMNSIP…
A0A397J0Q0 25-378 EKPVVYVGTVDFQEDLNKVAMRLSDMGEQCLKFINDNPNFQAKYRIEIRPDEDEWKLYLHLDPVAWFDALYPSEEETLLVKARKYVD…
A0A2Z6RN53 174-560 None
A0A2Z6RL25 126-387 None
A0A819Q462 55-429 None
A0A2Z6R321 15-257 None
A0A2Z6QJG7 1-282 None
A0A815NAQ1 34-298 None
A0A2P4PH05 11-370 None
A0A372RI67 56-360 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.