DPCstruct | MC62019

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)101 ± 13 aa
Standard deviation of domain lengths12.68
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score88.55
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)53.07
Pfam Score96.43
Assigned Pfam label(s) CL0020- CL0126

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6F9A994 8-99 KRSRERKRRIDGDRQIEVRHRWCELVVKHKYAQAYGDVEHFLIHDQAMGVYLYGELMVQEDSRQQALARRCLSLVQNEMDQSARRVV…
A0A4D9FCA2 38-128 LQCLEKTYHLDEQDAEVRHRWCELVVKHKYTTRYADIEKFLKEDQAMGVYLYGELMVNEDAKQQELAYKCFAATQKQMDVSSAKVVA…
A0A670Z312 218-327 None
H3A9Q3 51-162 None
L5K846 30-151 None
A0A7F8R8B4 93-198 None
A0A7M5WKU3 1025-1114 None
A0A5C6N0R4 115-215 None
R0LRG2 292-379 None
A0A7M7T3N7 444-556 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.