DPCstruct | MC62007

Metacluster Properties and Pfam Annotations

Number of structural domains100
Mean domain length (aa)124 ± 25 aa
Standard deviation of domain lengths24.75
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score86.14
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)16.70
Pfam Score76.28
Assigned Pfam label(s) PF14275- PF19546

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A073KFK8 20-143 VACSQSSSKIDKNNDVIAKGYKISNLHKFEKFALNVGNGEADKIRIVHYTDEGDPIFQTLEYDGKEVRYTSDDSHDKFAGTGKGIYS…
A0A2M9Q9V2 8-122 YSSEEAIENGDVVNLHGEISNLNRFESFIKNVENGAKDEIRITMYTIEGDPIFYNLNYNGDKIQYTYDNSQDEYAGTGKGIASTSCS…
F0STT0 13-187 None
A0A1M6YZU3 43-188 None
A0A2N3SGF6 82-196 None
A0A022LUL9 13-95 None
A0A5Q2VZL1 190-295 None
A0A1Q6K520 2-134 None
A0A2N0F4W4 19-131 None
A0A3A1QNK8 77-186 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.