DPCstruct | MC62002

Metacluster Properties and Pfam Annotations

Number of structural domains59
Mean domain length (aa)461 ± 78 aa
Standard deviation of domain lengths78.05
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score76.05
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.39
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)13.93
Pfam Score66.67
Assigned Pfam label(s) PF13448- CL0202

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Q6ZWK2 2-405 KLAELQRDRAKLQVDHYKALLAADISELEGKQLELLGLVSGLYLTAAELAAIPNLIVGLASGSIIDFAGTVSNVAQSIGTQASITAL…
A0A2S9YW84 2-272 AATIRLEIAERELDNHAKQVEHAQAVDAYMRTKFSNRELYDWMSSQLATLYFQTYQLAFDLAKRAERAYRHELAIDPAEPPIIEFGY…
A0A7R9W6W5 5-397 None
A0A6N0Z9Y8 11-326 None
A0A226F2A4 693-1148 None
A0A6P8I6F6 6-532 None
A0A3Q9D825 2-436 None
F8CEN2 719-1126 None
A0A835CS69 429-951 None
A0A2P2GX15 248-749 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.