DPCstruct | MC61975

Metacluster Properties and Pfam Annotations

Number of structural domains2319
Mean domain length (aa)188 ± 32 aa
Standard deviation of domain lengths31.96
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score83.03
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.41
Mean intra-cluster sequence similarity (%)15.60
Pfam Score94.97
Assigned Pfam label(s) CL0213- CL0020- PF00045- PF11901- CL0592

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q6EUS8 1-222 None
A0A7J7QNK6 2-179 None
A0A2E0MJX7 190-371 None
A0A401UEJ1 715-888 None
A0A6N2D7H1 134-322 None
A0A673GLV2 2-189 None
A0A3M0J242 698-928 None
A0A445EH71 90-275 None
A0A2E1W070 2-172 None
A0A853HAR2 13-178 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.