DPCstruct | MC61975

Metacluster Properties and Pfam Annotations

Number of structural domains2319
Mean domain length (aa)188 ± 32 aa
Standard deviation of domain lengths31.96
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score83.03
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.41
Mean intra-cluster sequence similarity (%)15.60
Pfam Score94.97
Assigned Pfam label(s) CL0213- CL0020- PF00045- PF11901- CL0592

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D4MJ24 259-439 None
A0A3P8WVL5 104-292 None
A0A2D6JMB6 60-223 None
A0A5C9CPD1 458-661 None
A0A6B0S6U6 6-112 None
A0A814GEX1 96-275 None
A0A814KBC9 2-162 None
A0A849EXN5 9-192 None
Q28S38 19-222 None
A0A353ZHF5 96-263 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.