DPCstruct | MC61975

Metacluster Properties and Pfam Annotations

Number of structural domains2319
Mean domain length (aa)188 ± 32 aa
Standard deviation of domain lengths31.96
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score83.03
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.41
Mean intra-cluster sequence similarity (%)15.60
Pfam Score94.97
Assigned Pfam label(s) CL0213- CL0020- PF00045- PF11901- CL0592

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E4X307 44-248 None
A0A2N2M4L5 2-144 None
A0A4S2R2G0 47-204 None
A0A0D2U1W4 225-478 None
M1CUQ0 410-580 None
A0A0R2MJX6 2-138 None
A0A813PXL4 114-273 None
E4X5Y1 55-302 None
A0A814B0K7 19-206 None
A0A354Z1A9 175-365 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.