DPCstruct | MC61975

Metacluster Properties and Pfam Annotations

Number of structural domains2319
Mean domain length (aa)188 ± 32 aa
Standard deviation of domain lengths31.96
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score83.03
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.41
Mean intra-cluster sequence similarity (%)15.60
Pfam Score94.97
Assigned Pfam label(s) CL0213- CL0020- PF00045- PF11901- CL0592

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A5XMB8 7-178 ECPRWSPGSVIRWSAWRQGFKTDEDAAFAADHLNMAAEKWNSLNIGVTFEWVPLAKDATFVLCHGGSHGGALAQAFFPNANDLNYLL…
Q8ZW37 2-154 RPRITVVAPSRIKPLEIPEFTTIWQFKDIDISHFLDLARGQCRADKVVEALSNGVKSPTVYVLDCDGYYPGLNFVFGLAVPVLKTAV…
A0A0S6W4H7 143-345 None
A0A0K0E6A2 7-163 None
A0A1H6CJA4 55-220 None
A0A0U3B8M8 14-182 None
A0A7Y1ZXS0 47-249 None
E7FAQ0 15-214 None
A0A1V6S3X7 3-178 None
A0A3N5G770 2-154 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.