DPCstruct | MC6197

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)576 ± 62 aa
Standard deviation of domain lengths61.72
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score80.20
Mean fraction of residues predicted as intrinsically disordered0.35
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)23.92
Pfam Score91.11
Assigned Pfam label(s) CL0023- CL0029- CL0110- CL0723- CL0197

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2P6TZZ8 8-535 VFRAGLLSTGEELKARYDASKPYPHCVIREFCNPDLLRKVRDEIIENVEATYKETDLFKMLQTGDLANMDALPAEQAAKLPTVRKLR…
A0A674F1Q1 2-464 RTAGFLDCQPFPHCIIRNFIQSDSFTENLQRELLDLNFHEKSNDLYKFNQSDDLKKRKEPHITGLRAALFGLFRSWLGEVLGVELEP…
K0THN4 44-639 None
A0A178F0X1 574-1241 None
A0A225AUP8 359-1008 None
A0A1S3J992 237-754 None
A0A5C6NN66 13-559 None
F1KZR8 19-539 None
A0A6A6P813 2-538 None
Q01F03 6-513 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.