DPCstruct | MC6191

Metacluster Properties and Pfam Annotations

Number of structural domains171
Mean domain length (aa)235 ± 56 aa
Standard deviation of domain lengths56.21
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score83.73
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)19.58
Pfam Score84.57
Assigned Pfam label(s) PF00410- CL0267- PF01000- CL0266- CL0198

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
I8TRZ7 1-287 MAEVPSVAIEFVFVHNNTSVIQDEVLAQRLGLIPLKGSVDGINWMRWFKKATEDDPEGSDPSDYNTIVLRLDIECTKNPNADATEND…
C4V9J5 2-224 KILIEESTDNIIKFTLRDTYVSYANALRRILISEVPTVTIDLVEIEINNTSLPDEMISHRLGLVPLYTKKDLVFRDDCACDDICDKC…
A0A5D2VIZ3 73-187 None
A0A6A5DR29 155-418 None
A0A3P8MUL4 8-312 None
A0A4Y1QC96 1-346 None
A0A446JIG1 117-242 None
A0A1B0C7F8 193-432 None
A0A2G8LDL2 51-251 None
A0A388NNQ7 6-135 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.