DPCstruct | MC61888

Metacluster Properties and Pfam Annotations

Number of structural domains65
Mean domain length (aa)120 ± 12 aa
Standard deviation of domain lengths12.01
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score80.87
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)25.23
Pfam Score98.15
Assigned Pfam label(s) PF14219- PF14018

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4U1HIW8 11-127 GGPPMEERSPVTLLALGFITCGIYYLIWKYQTTEELQRVSGDMTIKPGLDLLLTFVTCGVWAIYTDYRNAKKAHELFLSYGVNRPDR…
A0A355E515 9-120 AEYRHDIALGIILSIFTCGLYNIYWNYREFLAMNQLLGREEYRFWYWLGLTIITCGIFHIYYEYKMGSDLHDIIKGRGLEVNPNLAT…
A0A1V4WN23 74-190 None
D3Q459 40-157 None
A0A3A8V4I7 231-347 None
A0A497I5X0 26-129 None
A0A5R8QHY5 6-122 None
A0A4Q6F6G6 14-122 None
A0A1U7NQS0 4-116 None
A0A1Y4F5K7 40-163 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.