DPCstruct | MC61861

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)199 ± 12 aa
Standard deviation of domain lengths11.60
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score77.43
Mean fraction of residues predicted as intrinsically disordered0.35
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)43.82
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4R9E3M3 1-188 MRRRRPVRARTTLRAERLPGPGALYRLRVRTENTCVGVPAESGRDEALAHALIATHTFIGGEQVAFFSSIDPPEEVAEHTRDCANLH…
A0A7W1LB91 95-299 RGLEPLRDENEQIVGVIIRTQQEIFGVIELQVEEVSSQQLAISSQKLFKLTVRVKNLTALENAKEQSRDDALLHSLVSTHTILSATD…
A0A4Y8LVU0 27-226 None
A0A7V9PTH9 2-186 None
A0A1I2FFS0 77-251 None
A0A3N4STQ6 168-373 None
E3J6G0 211-405 None
A0A368VVG7 387-595 None
D6TEX2 127-329 None
A0A1M6PZT4 113-309 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.