DPCstruct | MC61848

Metacluster Properties and Pfam Annotations

Number of structural domains13243
Mean domain length (aa)252 ± 59 aa
Standard deviation of domain lengths58.75
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score82.51
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.36
Mean intra-cluster sequence similarity (%)14.23
Pfam Score71.92
Assigned Pfam label(s) PF01462- PF14484- CL0219- CL0010- PF01463

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H3H468 306-545 None
H3HBW5 4-248 None
A0A7I8VHN0 35-297 None
H3HBZ5 667-852 None
H3HCK7 13-235 None
A0A674IUK2 134-322 None
A0A2S8A4I7 15-237 None
A0A7S3SQ59 497-750 None
A0A7S3T6W2 54-339 None
A0A7S3TWT7 558-849 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.