DPCstruct | MC61848

Metacluster Properties and Pfam Annotations

Number of structural domains13243
Mean domain length (aa)252 ± 59 aa
Standard deviation of domain lengths58.75
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score82.51
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.36
Mean intra-cluster sequence similarity (%)14.23
Pfam Score71.92
Assigned Pfam label(s) PF01462- PF14484- CL0219- CL0010- PF01463

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A2DIM0 109-283 None
A2E090 177-530 None
A0A2P1QWH2 29-169 None
A0A6P4PV88 252-495 None
D3EYV8 71-272 None
A0A2P5XWG8 2-181 None
A2D8A0 302-597 None
A0A2H5SHE1 106-433 None
A0A2Z6M8C3 306-597 None
A0A2Z6LWH1 201-558 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.