DPCstruct | MC61848

Metacluster Properties and Pfam Annotations

Number of structural domains13243
Mean domain length (aa)252 ± 59 aa
Standard deviation of domain lengths58.75
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score82.51
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.36
Mean intra-cluster sequence similarity (%)14.23
Pfam Score71.92
Assigned Pfam label(s) PF01462- PF14484- CL0219- CL0010- PF01463

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E2AGL2 801-1056 None
A0A6M5EMS4 77-360 None
C4YVR9 179-473 None
A0A2E6TTT9 80-261 None
A0A4Z2C795 280-553 None
A0A4Z2CBB9 240-477 None
A0A250E2G2 174-362 None
A0A671WQ75 430-656 None
A0A811YFF3 20-209 None
L1JFL7 723-1012 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.