DPCstruct | MC61821

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)105 ± 11 aa
Standard deviation of domain lengths10.66
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score81.99
Mean fraction of residues predicted as intrinsically disordered0.43
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.89
Mean intra-cluster sequence similarity (%)73.86
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4D6LLH1 167-273 AKAVAEYQYPWREKLVKYKDELAKGVWGYWDLGAWKPLSISARRRARLRKEVLLTGEDWPYDPERKEMKTRRKGHKCDRISAEKREN…
A0A388KNE4 6-102 EAQLAAGLKRLAAKVKPTWFNGKFVGTDMSAKNIARVRRQVLLVGEEWPYDKPRKEMKTRVKGHKVDRIAQAKREKTKELMEQMPQL…
A0A3L6RBA2 9-115 None
A0A452XP74 8-112 None
A0A4D9C323 28-139 None
A0A453REN1 4-93 None
A0A453RE17 2-94 None
A0A2R6RMJ2 69-182 None
A0A5J5B497 513-611 None
A0A7J9E2V4 1-116 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.