DPCstruct | MC6174

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)143 ± 9 aa
Standard deviation of domain lengths8.92
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score84.22
Mean fraction of residues predicted as intrinsically disordered0.15
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)30.50
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E3R5J6 92-228 EKIIEWSTIFEDKQIYIQKLQTIDWLTAKQIQFLQNIRLQGWGRLSKKLLTAIVDSNGQNIIEQLWNSQQIFMSIVNKADIKGTITD…
A0A0B7GZY0 2-149 WASIYDEGEGRKILEAKIQSVYPDVFTQDELNKILKLKISGWGRFSRKFLESIVTPFPGFTDTINIITAMRETNFNLMELLGDAYGF…
A0A6P4L7E9 55-196 None
E9S0G5 239-367 None
A0A416PQJ1 48-195 None
A0A0X8KN88 494-643 None
A0A1H7I2G4 106-255 None
A0A412L4T3 18-136 None
A0A2S3U2K5 252-399 None
H1D477 105-252 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.