DPCstruct | MC61728

Metacluster Properties and Pfam Annotations

Number of structural domains111
Mean domain length (aa)245 ± 53 aa
Standard deviation of domain lengths52.88
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score80.35
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)18.64
Pfam Score47.53
Assigned Pfam label(s) PF15612- CL0125- PF02791- PF15613

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A7RH53 5-225 IRSWWEVPSIAHFCSLFRTAFGLTDFEIEDLEDALLLDGSKEDSYNRFLADLHASLLKGLFTGNKDINADNFEPYLSEVLKIRWQDE…
A0A6A0H7Y3 4-131 VSPVIVQLVLLLLRKLNRATKIDRWEKALQRFAHLHSLKDGWELERFGFKQAQLEVKIRVLKNLFEALFDSCKSFKDKINGLAAREL…
A0A453E8I2 2-194 None
A0A820CZ10 52-311 None
K3WKR2 2-149 None
K3WZ96 211-514 None
M1WBM7 10-291 None
A0A1E4SCI0 35-379 None
A0A6P5MLT3 21-301 None
A0A287I028 10-206 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.