DPCstruct | MC61674

Metacluster Properties and Pfam Annotations

Number of structural domains52
Mean domain length (aa)256 ± 42 aa
Standard deviation of domain lengths41.61
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score81.58
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)41.57
Pfam Score100.00
Assigned Pfam label(s) CL0111

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A287VWC0 3-248 VPTNLEARRRISFFTNSLFMEMPRAPRVRKMLSFSVMTPYYSEETVYSRNDLDLENEDGVSIIFYLQKIFPDEWNNFMERISCKREA…
A0A1D6GWW7 1-172 MAQEPLLEPMLLYTILTPYYKEDVLFSLQNLEERNEDGVSILFYLQKIYPDEWKNFLERVGCKNEEVLREDEQLEEKLCLWVSYRGQ…
A0A445I842 220-393 None
A0A812M2C4 488-823 None
A0A287TSD6 244-509 None
A0A453DH04 18-202 None
A0A6A3UIE4 40-288 None
A0A0L9V9W1 334-604 None
A0A7S2JUY3 52-435 None
A0A287PW09 834-1120 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.