DPCstruct | MC616

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)156 ± 13 aa
Standard deviation of domain lengths13.11
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score84.76
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)38.41
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0N4WTQ4 76-227 TDLLASIELDWVALSRREPDDEQSHVLYSSLMIALSRLALTECGWNTLAELALPEVLAELRVFSNPPKQMFLEPASVKKKGSPAELY…
A0A0B1SDR1 1-156 MTDLLASVKMDWTALSKGDPEALHIYGLFKSLMLTLTRLSLTESGWNALAELALPEVLAQLQMFVSPPKEVFLQPASVKEKNSVGEL…
A0A183HDX0 55-207 None
A0A183FSZ6 3-162 None
W2SRP2 66-203 None
G0NR56 124-285 None
A0A0D8XCV8 2-156 None
K7HXF2 4-142 None
A0A0N4UDS2 54-211 None
A0A2A2JVW2 84-271 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.