DPCstruct | MC61588

Metacluster Properties and Pfam Annotations

Number of structural domains349
Mean domain length (aa)221 ± 47 aa
Standard deviation of domain lengths46.78
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score78.89
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)16.07
Pfam Score99.05
Assigned Pfam label(s) CL0758- PF10283- CL0004- CL0028- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y2DZX5 3-148 None
A0A4Z2CEE3 165-381 None
A0A445DWT1 30-189 None
A0A1L7TM42 226-510 None
A0A3R7XB50 214-488 None
A0A3M6VQG7 2-174 None
M7T2I9 1-281 None
A0A1Y1I5G6 25-252 None
A0A1Y1I4M7 8-267 None
A0A349PIS8 7-189 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.